Tag Archives: breast-cancer

Early Breast Cancer Detection – An enhanced EIT technique

Electrical Impedance Tomography (EIT) is an emerging medical imaging technique that creates pictures of the inner structures of the body in a completely safe, non-invasive way. It works by gently applying small, imperceptible electrical currents on the skin using electrodes. As these currents pass through body tissues, they encounter different levels of impedance – resistance to electrical flow – which manifests as voltages measured again on the skin. Unlike X-rays or MRIs, EIT does not require potentially harmful ionizing radiation or magnets.

Since cancerous growths have different cell structures and water content compared to healthy tissues, they conduct electricity differently. By using algorithms to convert many skin voltage measurements around the body into an image, EIT can map these electrical property differences. This allows benign and malignant tumors – and even microcalcifications – to be distinguished clearly without recalls or biopsies.

EIT is still an early-stage technology, but its unique ability to harmlessly “see” tissue structure and composition shows enormous promise. Integrating it with phased array engineering now enables more advanced, higher resolution images able to change cancer diagnostics. The safe, comfortable and affordable EIT examination may one day become a routine part of healthcare.

Limitations of Current Diagnostic Tools

The most common breast cancer diagnostic tools face considerable limitations. Mammograms use harmful ionizing radiation and painful compression. Their resolution is insufficient to catch early tumors, frequently generating false positives that lead to stressful and unnecessary follow-up tests and biopsies. Ultrasounds rely heavily on operator skill and struggle to penetrate dense breast tissue. Dynamic contrast MRIs require the injection of contrast dye agents which are expensive and can cause allergic reactions or kidney damage. These tools also involve long scan times and accessibility issues for many patients. Unlike these imaging modalities, phased array EIT offers high resolution 3D maps of breast tissue in a comfortable, non-toxic way using only safe levels of electrical current. The sensitivity of impedance mapping may allow for diagnoses without recalls or biopsies. As an affordable technology that requires no chemicals or radiation, phased array EIT has the potential to complement and enhance the entire pipeline of breast cancer detection for all patients.

Reimagining the Future of Breast Cancer Diagnosis:

The Promise of Phased Array EIT In an era when one in eight women will develop breast cancer in their lifetime, early and accurate detection remains impeded by suboptimal diagnostic tools that expose patients to harm while still struggling to discern tumors at the most treatable stages. However, a new approach promises to revolutionize how we image, screen and ultimately save the lives of those at risk of cancer. By integrating phased array technology with Electrical Impedance Tomography (EIT), a non-invasive current-imaging technique, researchers have paved an avenue to dramatically enhance EIT’s resolution and utility in mapping the subtle electrical signatures of malignant tissues—all while avoiding the downsides of existing cancer diagnostic pipelines.

How Phased Array EIT Achieves a New Level of Clarity
Phased array EIT centers around the use of a configurable grid of transmitter and receiver electrodes that steer localized clusters of current pulses dynamically in and around target tissues. By subtly manipulating the shape, directionality and synchronization of these clusters, the system generates fine-grained three-dimensional impedance maps with previously unattainable detail down to the level of microcalcifications and tumor angiogenesis. At the same time, advanced computational algorithms reconstruct artefact-free images from multifaceted data gathered through the technique’s elegant and intricate current steering approach.

Phased array EIT improves resolution through the use of multiple transmitting and receiving electrodes that can manipulate the shape, timing, and directionality of electrical current pulses. By subtly and rapidly altering the phase relationships between electrodes, the resulting constructive and destructive interference patterns can be used to focus current into tighter beams that scan across smaller regions of tissue. This allows more discrete sampling and mapping of impedance properties. Advanced algorithms can then reconstruct high-resolution images reflecting anomalies. Compared to conventional EIT with fixed electrode configurations and diffuse current patterns, phased array EIT enables superior focusing and targeting of cancerous tissues while also gathering robust data through its dynamic pulses. With hundreds of sensing elements that can pulse in intricate patterns, detailed 3D maps of the electrical properties of breast tissue can be built to reveal tumors or microcalcifications invisible to other modalities.

When integrated into a practical, patient-comfortable examination device, phased array EIT promises detection specificity and sensitivity well beyond seen in error-prone mammograms, operator-dependent ultrasounds, and toxic contrast MRIs. The affordability and safety profile empowers patients to monitor their breast health more frequently and catch the subtle changes that so often escalate into late stage disease with current modalities handicapped by their cost and access barriers. With further research and innovation, guided electrical scanning via phased arrays could salvage and transform the difficult diagnostic odyssey millions embark on each year.

Realizing the Potential Through Collaboration

Still, harnessing the full capability of phased array EIT requires breaking down knowledge silos and embracing multidisciplinary perspectives. Engineers, computational experts, clinicians and public health leaders must bridge their efforts to assess needs, prototype designs and analyze clinical outcomes. Funding and partnerships between academics, non-profits and industry can accelerate this effort. And active engagement with patients is critical for addressing real-world diagnostic challenges in an ethical, sensitive way. By recognizing each stakeholder’s unique yet unified role in this endeavor, a technology once restricted to radar systems could soon guide breast cancer care into an era where saving lives is no longer impeded by the tools meant to safeguard them.

Smart ultrasound bra for early breast cancer detection

This is now incorporated in my thoroughly rewritten and greatly improved blog on Femtech: https://timeguide.wordpress.com/2023/12/29/more-femtech/ but I’ll leave it here since that full version is 10k words now.

Breast Health Monitoring Bra – Detecting Cancer Early Through AI-Powered Ultrasound

This is an overdue update of my 2015 idea.

Breast cancer afflicts nearly 1 in 8 women in their lifetime. Despite advances in treatment, early detection remains key to survival. Unfortunately, 50% of breast lumps are still self-detected instead of via clinical screenings, resulting in later diagnosis. We need better tools for consistent monitoring.

I propose developing a smart bra integrated with ultrasound transducers to enable continuous breast health tracking. Rather than relying on manual self-exams, the bra’s ultrasound scans fed into a personalized AI algorithm could identify the earliest anomalies, like small lumps. Catching cancers at the onset drastically improves prognoses.

I don’t envisage a woman wearing such a bra all day, but wearing it for a weekly check, maybe 5-10 minutes, just as she might perform her own regular blood pressure tests using an armband device.

While ultrasound imaging has difficulties with dense breast tissue, advancements like elastography and contrast-enhanced ultrasound continue expanding its capabilities. As the technology progresses, integrating these improvements into smart bras could widen detection potential.

The ultrasound bra would contain an array of miniaturized transducers around each cup to image the breast tissue. The AI would employ a convolutional neural network architecture, trained on thousands of ultrasound images to identify visual patterns predictive of breast abnormalities. Through continuous learning as more user data is gathered, the accuracy of classification and anomaly detection will evolve.

But it wouldn’t just use generalised data. The AI model would learn the unique ultrasound patterns of healthy breasts for each woman. Wearing the bra weekly for 5-10 minutes would allow the AI to compare new scans and highlight slightest abnormalities, triggering alerts for further testing.

Beyond early cancer detection, the monitoring capacity can prove useful for tracking tumors post-diagnosis, measuring treatment effectiveness, and surveillance of high-risk cases.

Ultrasound is safer than radiation-based scans. Comfort-focused design would make adoption feasible as part of a regular routine for women. Targeting the 40+ age demographic at higher risk could make lifesaving impact.

Key technical challenges include crafting accurate AI training protocols, minimizing device bulk, and protecting sensitive medical data. User feedback must inform development to address privacy and accessibility barriers.

The ultrasound bra’s innovation lies in transforming breast screening into a convenient, non-invasive process proactively managed by AI. Moving beyond manual checks, it promises earlier detection when treatment is more effective. With research and empathy guiding engineering, this femtech invention could save many lives.

To augment early detection, the bra could contain Bluetooth connectivity to link with smartphone health apps. This would allow the AI algorithm to deliver breast health insights directly to the user for at-home monitoring while also enabling seamless sharing of the ultrasound data with clinicians.

To address privacy concerns, ultrasound data is securely encrypted and stored locally on the bra’s integrated chip, with access controlled by the user. Data is only shared to external apps and clinicians with explicit consent through HIPAA-compliant channels.

For expert analysis, the AI could generate detailed imaging records and mapping of the breast tissue. Comparing this medical-grade documentation against past scans would allow radiologists to interpret even minute abnormalities. Remote testing protocols could also be built-in for specialists to prescribe more targeted ultrasound tests for follow-up.

By bridging both consumer and clinical spaces, the smart bra aids self-tracking while integrating with the healthcare system for elevated risk cases. Direct user education combined with streamlined physician access to ultrasound records helps ensure no early warning sign is missed. Capturing advantages on both ends will be key for saving lives.